Published: Jun 24, 2026
Published: Jun 23, 2026
Published: Jun 24, 2026
Published: Jun 24, 2026
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Authors: Hayslip N, Kim J, Ashiqueali SA, Zhu X, Hussein R, Alam MT, Garcia DN, Zanini BM, Kubik A, Allen N, Blaber EA, Siddiqi SS, Mansoor MAM, Schisler JC, Mason CE, Beheshti A, Masternak MM Abstract Future deep-space missions will expose astronauts to microgravity and ionizing radiation, which induce molecular changes that mirror biological aging,... <a class="view-article" href="https://pitt.creatotech.com/space-radiation-and-microgravity-as-models-of-accelerated-aging-modulation-of-hepatic-mirna-tgf-%ce%b2-networks-associated-with-senescence-and-fibrosis/">View Article</a>
Read MoreAuthors: Tamama K, Faust A, Lin FP, Qu L, DiMartini AF PMID: 42302240
Read MoreAuthors: Abou Chakra M, Hislop J, Egilmez I, Alkalai R, Bashth O, Maheden K, Gundagathi A, Ebrahimkhani MR, Shakiba N Abstract While cells are driven to preserve their own survival, they must cooperate to ensure embryo viability. To explore how cellular behaviours shape human development, we intersect evolutionary game theory and in vitro embryo modelling.... <a class="view-article" href="https://pitt.creatotech.com/the-embryo-game-uncovers-hidden-cell-behaviours/">View Article</a>
Read MoreAuthors: Yang R, Haykal T, Tohme C, He Z, Zhang H, Gebran A, Liu S, Simmons RL, Geller DA, Yazdani HO, Tohme S Abstract Tumor-derived exosomes contribute to the formation of a hepatic pre-metastatic niche (PMN) by activating Kupffer cells (KCs) and hepatic stellate cells (HSCs), thereby promoting metastatic seeding. Whether exercise modulates exosome-driven PMN... <a class="view-article" href="https://pitt.creatotech.com/exercise-reduces-hepatic-pre-metastatic-niche-formation-via-trem-1-signaling-in-kupffer-cells/">View Article</a>
Read MoreAuthors: Swanson WB, Wu DT, Yoshida M, Ambruster J, Sfeir CS, Wagner WR, Mooney DJ, Giannobile WV, Kohn DH Abstract Dental, oral, and craniofacial regenerative medicine has benefitted from fundamental scientific discoveries, yet the resulting technologies and therapies do not always generate the anticipated clinical impact. Despite robust progress and substantial investment in biomaterials and... <a class="view-article" href="https://pitt.creatotech.com/driving-emerging-technology-to-clinical-impact/">View Article</a>
Read MoreAuthors: Edmunds KJ, Porter EC, Lai YR, Guyette J, Williams C, Jaiganesh A, Ott H, Weinbaum JS, Black LD Abstract The development of regenerative strategies to repair the heart is of high importance. Our lab has shown that extracellular matrix derived from decellularized fetal myocardium promotes neonatal cardiomyocyte proliferation in vitro. The goal of this... <a class="view-article" href="https://pitt.creatotech.com/identification-and-characterization-of-a-fibrillin-1-derived-matrikine-for-cardiac-regeneration-and-repair/">View Article</a>
Read MoreAuthors: Schreib CC, Kelley EL, Audia G, Garg R, Johnson S, Fleury S, Behun MN, Vohidova D, Kulkarni M, Donnell GM, Brown BN, Badylak SF, Cohen-Karni T, Veiseh O Abstract Wounds can become chronic if the biological processes that coordinate tissue repair, including immune cell activity and matrix remodelling, become dysregulated. Current treatments mainly focus... <a class="view-article" href="https://pitt.creatotech.com/cell-based-cytokine-patch-for-localized-immunomodulation-and-accelerated-healing-in-rodent-and-porcine-wounds/">View Article</a>
Read MoreAuthors: Wu B, Castagnola E, Robbins E, Kaminsky M, Sanker S, McClung CA, Cui XT Abstract The circadian rhythm regulates physiological and behavioral processes, with disruptions linked to metabolic and neuropsychiatric disorders. Circadian genes play a crucial role in the regulation of dopaminergic signaling, yet the underlying molecular mechanisms remain unclear. This study investigates how... <a class="view-article" href="https://pitt.creatotech.com/tonic-dopamine-sensing-reveals-a-d2-and-d3-mediated-dopamine-response-to-raclopride-in-%ce%b4-mice-model/">View Article</a>
Read MoreAuthors: Borrelli MA, Warunek JJP, Ann Varghese B, Turner N, Little SR, Turnquist HR Abstract Skeletal muscle injuries are a common consequence of physical activity, repetitive movements, and trauma. Regulatory T cells (Treg) act as critical mediators of immune repair response after injury. Thus, treatments effectively targeting Treg may accelerate injury resolution. CCL22 is a... <a class="view-article" href="https://pitt.creatotech.com/regulatory-t-cell-attracting-therapy-accelerates-skeletal-muscle-functional-recovery-following-injury/">View Article</a>
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